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1,10-Phenanthroline, Monohydrate

●Purchase●Description1,10-phenanthroline(o-phenanthroline)isachelatorwithhighaffinityfordivalentmetalions

  • 產(chǎn)品型號(hào)：27713
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時(shí)間：2023-12-19
  • 訪  問(wèn)  量：316
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1,10-phenanthroline (o-phenanthroline) is a chelator with high affinity for divalent metal ions. When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions. While not specific for DUBs, it has been shown to be a potent inhibitor of JAMM-type isopeptidases through chelation of the active site Zn2+ ion. As such, o-phenanthroline is widely used when preparing cell lysates for enrichment of proteins bearing K63-linked polyubiquitin chains which are especially sensitive to DUBs in the JAMM family.

This product has been cited 2 times.

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Synonyms
o–phenanthroline
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