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TMPRSS2 Lentivirus

保存條件:-80°C(dryice)保質期:3-18month英文名:TMPRSS2Lentivirus數(shù)量:1供應商:BPSBioscienceInc

  • 產品型號:
  • 廠商性質:生產廠家
  • 更新時間:2023-10-11
  • 訪  問  量:167
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詳細介紹
  • 保存條件:

    -80°C (dry ice)

  • 保質期:

    3-18 month

  • 英文名:

    TMPRSS2 Lentivirus

  • 數(shù)量:

    1

  • 供應商:

    BPS Bioscience Inc.

  • CAS號:

    /

  • 規(guī)格:

    100 µl

Human transmembrane serine protease 2 (TMPRSS2) is an enzyme primarily expressed by endothelial cells across the respiratory and digestive tracts. It is involved in viral entry and spread of coronaviruses including SARS-CoV-2, the virus that causes COVID19. TMPRSS2 primes the spike protein by cleaving at the S1/S2 site, leading to the virus fusing to the respiratory epithelia on the cell surface through binding to ACE2. Blocking TMPRSS2 activity could potentially be an effective clinical therapy for .
The TMPRSS2 Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an TMPRSS2 gene (NM_005656.4) driven by an EF1a promoter.
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